Welcome
At the Kovari Group, we are interested in the molecular mechanisms of HIV-1 resistance to FDA approved inhibitors. Our laboratory specializes in the structural and biological analysis of proteins using structure-function studies to investigate pharmacological drug targets against HIV-1 and Hepatitis C viruses. Our areas of expertise include biochemistry, molecular biology, pharmacology, and structural biology. Project protocols involve protein expression and purification, crystallization, structure determination, Inhibitor IC50 and Ki measurements, protein stability, molecular dynamics and ligand binding measurements.