School of Medicine

Wayne State University School of Medicine


At the Kovari Group, we are interested in the molecular mechanisms of HIV-1 resistance to FDA approved inhibitors. Our laboratory specializes in the structural and biological analysis of proteins using structure-function studies to investigate pharmacological drug targets against HIV-1 and Hepatitis C viruses. Our areas of expertise include biochemistry, molecular biology, pharmacology, and structural biology. Project protocols involve protein expression and purification, crystallization, structure determination, Inhibitor IC50 and Ki measurements, protein stability, molecular dynamics and ligand binding measurements.

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Dr. Ladislau C. Kovari Wayne State University School of Medicine Dept. of Biochemistry and Molecular Biology 540 E. Canfield Avenue Detroit, MI 48201
E-mail: Tel: 313-577-0296 (lab) Tel: 313-993-1335 (office) Fax: 313-577-2765